1. After getting the necessary software and license from IBM Academic Initiative, you should install the CPLEX binary
# ./cplex_studio122.acad.linux-x86.bin
2. For the license file, make use your license file name is "access.ilm" (without the quotation)
3. Create a folder to house the license. CPLEX needs this folder to be present
# mkdir -p /usr/ilog/ilm
# mv access.ilm /usr/ilog/ilm
4. You should be able to run your CPLEX now. To verify, go to the CPLEX binary folder and run it. In my case
# /usr/local/cplex_studio_122/cplex/bin/x86-64_sles10.4.1/cplex
5. To install the Python API of CPLEX, do read up on IBM iLOG Optimization Studio Documentation
# cd /usr/local/cplex_studio_122/cplex/python/x86-64_sles10_4.1/
# python setup.py install --home ./cplex/
You will need to add the path to your PYTHONPATH by running
export PYTHONPATH=$PYTHONPATH:/usr/local/cplex_studio_v12/cplex/python/x86-64_sles10_4.1