The Rosetta software focuses on the prediction and design of protein structures, protein folding mechanisms, and protein-protein interactions. Rosetta codes consistently exhibit repeated success in the Critical Assessment of Techniques for Protein Structure Prediction (CASP) competition as well as the CAPRI competition. Rosetta codes also address aspects of protein design, docking and structure. The software is the foundation for the Human Proteome Folding Project on the World Community Grid.
The Rosetta software is currently licensed for free to users at academic and nonprofit institutions. Over 2000 academic users in more than 32 countries use Rosetta. Commercial entities can use Rosetta by paying a license fee. Revenue from licensing is reinvested in supporting continued software development.
